Leadbeaterin-2

Sterolysins

Last updated at: Sept. 23, 2026

Recommended name
Leadbeaterin-2
Synonyms
n/a
Recommended acronym
n/a
Abbreviation

Progenitors

Name
Chrysochromulina leadbeateri
Note
Identified by LC-HRMS in C. leadbeateri cultures and Norwegian field samples from 2019 and 2025 associated with fish mortalities. Cultures of strains isolated from the 2019 fish-killing bloom were toxic in gill cell bioassays and contained leadbeaterins 1 to 6

Vector Species

No vector species registered

References

Wang et al., 2024
Wang, X.; Fon, M.; Andersen, A. J. C.; Solhaug, A.; Ingebrigtsen, R. A.; Samdal, I. A.; Uhlig, S.; Miles, C. O.; Edvardsen, B.; Larsen, T. O. Insights into the nature of ichthyotoxins from the Chrysochromulina leadbeateri blooms in Northern Norwegian fjords. Harmful Algae 2024, 137, 102681.
Wang et al., 2026
Wang, X.; Solhaug, A.; Mudge, E. M.; Garrido, B. C.; Fon, M.; Andersen, A. J. C.; Solhaug, A.; Samdal, I. A.; Edvardsen, B.; McCarron, P.; Gotfredsen, C. H.; Hansen, P. J.; Miles, C. O.; Larsen, T. O. Structure elucidation of leadbeaterin-1, and ichthyotoxin associated with fish-killing Chrysochromulina leadbeateri blooms in northern Norwegian Fjords. Harmful Algae 2026, 156, 103104.
Structure
Formula
C67H125ClO27
Exact mono-isotopic mass
1396.80968
Molfile
n/a
Alternative molfiles
n/a
SMILES
Alternative SMILES
n/a
InChi key
Alternative InChi keys
n/a
InChi
Alternative InChis
Spectra available
Unknown
Chem files
Certified
False
Certified links
    n/a
Non certified reference material
False

Chemical analysis

Research
True
Standardized
False
Validated
False
Official
n/a

Structure recognition assays

Research
False
Standardized
False
Validated
False
Official
n/a

Functional assays

Research
Unknown
Standardized
Unknown
Validated
Unknown
Official
n/a

Animal assays

Research
Unknown
Standardized
Unknown
Validated
Unknown
Official
n/a
Regulatory status
Unknown
Human toxic syndrome(s)
n/a
Organ system toxicity
n/a
Risk assessment
Unknown
Molecular targets known
Unknown
Molecular targets
n/a
Toxic to aquatic animals
True
TEF available
Unknown
Notes
Structure not yet elucidated, identified by LC-HRMS
Christopher Miles
Contact