Saxitoxin

Saxitoxin

Last updated at: Nov. 5, 2023

Recommended name
Saxitoxin
Synonyms
Saxidomus giganteus poison, Gonyaulax catenella poison, Mytilus californianus poison
Recommended acronym
STX
Abbreviation
Structure
Formula
C10H17N7O4
Exact mono-isotopic mass
299.13420205
Molfile
n/a
Alternative molfiles
n/a
SMILES
O=C(OC[C@@H]2/N=C(/N)N3[C@]1(/N=C(\N[C@H]12)N)C(O)(O)CC3)N
Alternative SMILES
n/a
InChi key
RPQXVSUAYFXFJA-HGRQIUPRSA-N
Alternative InChi keys
n/a
InChi
1S/C10H17N7O4/c11-6-15-5-4(3-21-8(13)18)14-7(12)17-2-1-9(19,20)10(5,17)16-6/h4-5,19-20H,1-3H2,(H2,12,14)(H2,13,18)(H3,11,15,16)/t4-,5-,10-/m0/s1
Alternative InChis
Spectra available
True
Chem files
chemfiles/STX.cdxml
Certified
True
Certified links
    n/a
Non certified reference material
True

Chemical analysis

Research
True
Standardized
True
Validated
True
Official
CEN EN 14526:2017

Structure recognition assays

Research
Unknown
Standardized
Unknown
Validated
Unknown
Official
n/a

Functional assays

Research
True
Standardized
True
Validated
Unknown
Official
AOAC Official Method 2011.27

Animal assays

Research
True
Standardized
True
Validated
False
Official
AOAC Official method 959.08
Regulatory status
True

References

, 2004
Regulation (EC) 853/2004 of the European Parliament and the Council of 29 April 2004 laying down specific hygiene rules on the hygiene of foodstuffs. Official Journal of the European Union. L139/55.
Human toxic syndrome(s)
Paralytical Shellfish Poisoning
Organ system toxicity
Neurotoxicity, Gastro-intestinal toxicity
Risk assessment
True
Molecular targets known
True
Molecular targets
Voltage dependent sodium channel (site 5), Voltage dependent sodium channel (site 1)
Toxic to aquatic animals
True
TEF available
True

TEF References

, 2009
EFSA (European Food Safety Authority) 2009. “Scientific opinion of the panel on contaminants in the food chain on a request from the European Commission on marine biotoxins in shellfish-saxitoxin group,” European Food Safety Authority Journal, vol. 1019, pp. 1–76.
Notes
Maria Joao Botelho
Contact