Cylindrospermopsin

Cylindrospermopsin

Last updated at: Oct. 23, 2023

Recommended name
Cylindrospermopsin
Synonyms
n/a
Recommended acronym
CYN
Abbreviation

Progenitors

Name
Lyngbya
Note
Currently Accepted: Microseira wollei Synonym: Lyngbya wollei First evidence for the production of cylindrospermopsin and deoxy-cylindrospermopsin by the freshwater benthic cyanobacterium, Lyngbya wollei (Farlow ex Gomont) Speziale and Dyck Phylogeny and toxicology of Lyngbya wollei (Cyanobacteria, Oscillatoriales) from north-eastern Australia, with a description of Microseira gen. nov.
Name
Aphanizomenon
Note
Species: Aphanizomenon ovalisporum Identification of cylindrospermopsin in Aphanizomenon ovalisporum (Cyanophyceae) isolated from Lake Kinneret, Israel
Name
Raphidiopsis raciborskii
Note
Currently Accepted: Raphidiopsis raciborskii Synonym: Cylindrospermopsis raciborskii Isolation and identification of the cyanotoxin cylindrospermopsin and deoxy-cylindrospermopsin from a Thailand strain of Cylindrospermopsis raciborskii (Cyanobacteria) HPLC-PDA-UV HPLC-MS/MS Identification of genes implicated in toxin production in the cyanobacterium Cylindrospermopsis raciborskii HPLC-MS Interspecific allelopathy in cyanobacteria: Cylindrospermopsin and Cylindrospermopsis raciborskii effect on the growth and metabolism of Microcystis aeruginosa
Name
Anabaena
Note
Species: Anabaena lapponica First observation of cylindrospermopsin in Anabaena lapponica isolated from the boreal environment (Finland) HPLC-DAD HPLC-MS/MS HPLC-TOFMS
Name
Raphidiopsis curvata
Note
First report of the cyanotoxins cylindrospermopsin and deoxycylindrospermopsin from Raphidiopsis curvata (Cyantobacteria)
Name
Aphanizomenon flosaquae
Note
First report on cylindrospermopsin producing Aphanizomenon flos-aquae (Cyanobacteria) isolated from two German lakes HPLC-MS/MS
Name
Kamptonema
Note
Shishido TK, Delbaje E, Wahlsten M, Vuori I, Jokela J, Gugger M, Fiore MF, Fewer DP. A cylindrospermopsin-producing cyanobacterium isolated from a microbial mat in the Baltic Sea. Toxicon. 2023 Aug 15;232:107205. doi: 10.1016/j.toxicon.2023.107205. Epub 2023 Jul 3. PMID: 37406865.

Vector Species

No vector species registered

References

Harada, K., 1994
Isolation of cylindrospermopsin from a cyanobacterium Umezakia natans and its screening method
Banker, R., 2008
Identification of cylindrospermopsin in Aphanizomenon ovalisporum (Cyanophyceae) isolated from Lake Kinneret, Israel
Li, R., 2002
First report of the cyanotoxins cylindrospermopsin and deoxycylindrospermopsin from Raphidiopsis curvata (Cyantobacteria)
Li, R., 2001
Currently Accepted: Raphidiopsis raciborskii Synonym: Cylindrospermopsis raciborskii Isolation and identification of the cyanotoxin cylindrospermopsin and deoxy-cylindrospermopsin from a Thailand strain of Cylindrospermopsis raciborskii (Cyanobacteria) HPLC-PDA-UV HPLC-MS/MS
Preußel, K., 2006
First report on cylindrospermopsin producing Aphanizomenon flos-aquae (Cyanobacteria) isolated from two German lakes HPLC-MS/MS
Schembri, M.A., 2001
Currently Accepted: Raphidiopsis raciborskii Synonym: Cylindrospermopsis raciborskii Identification of genes implicated in toxin production in the cyanobacterium Cylindrospermopsis raciborskii HPLC-MS
Spoof, L., 2006
First observation of cylindrospermopsin in Anabaena lapponica isolated from the boreal environment (Finland) HPLC-DAD HPLC-MS/MS HPLC-TOFMS
Seifert, M., 2007
Currently Accepted: Microseira wollei Synonym: Lyngbya wollei First evidence for the production of cylindrospermopsin and deoxy-cylindrospermopsin by the freshwater benthic cyanobacterium, Lyngbya wollei (Farlow ex Gomont) Speziale and Dyck
Rzymski, P., 2014
Currently Accepted: Raphidiopsis raciborskii Synonym: Cylindrospermopsis raciborskii Interspecific allelopathy in cyanobacteria: Cylindrospermopsin and Cylindrospermopsis raciborskii effect on the growth and metabolism of Microcystis aeruginosa
McGregor G.B., 2014
Currently Accepted: Microseira wollei Synonym: Lyngbya wollei Phylogeny and toxicology of Lyngbya wollei (Cyanobacteria, Oscillatoriales) from north-eastern Australia, with a description of Microseira gen. nov.
Structure
Formula
C15H21N5O7S
Exact mono-isotopic mass
415.116172
Molfile
n/a
Alternative molfiles
n/a
SMILES
O[C@H](C(N=C(O)N1)=CC1=O)[C@](C2)([H])[nH][c+]3[nH]C[C@]4([H])[C@@H](C)[C@@H](OS(=O)([O-])=O)C[C@@]2([H])n43
Alternative SMILES
n/a
InChi key
LHJPHMKIGRLKDR-VDPNAHCISA-N
Alternative InChi keys
n/a
InChi
InChI=1S/C15H21N5O7S/c1-6-10-5-16-14-17-8(13(22)9-4-12(21)19-15(23)18-9)2-7(20(10)14)3-11(6)27-28(24,25)26/h4,6-8,10-11,13,22H,2-3,5H2,1H3,(H,16,17)(H,24,25,26)(H2,18,19,21,23)/t6-,7+,8-,10-,11+,13-/m1/s1
Alternative InChis
Spectra available
Unknown
Chem files
Certified
True
Certified links
  • National Research Council Canada
    Contact us Halifax CRM Sales Office Metrology Research Centre 1411 Oxford Street Halifax, Nova Scotia B3H 3Z1 Telephone: 902-426-8281 Fax: 902-426-5426 Email: CRM-MRCHalifax@nrc-cnrc.gc.ca
Non certified reference material
True

Chemical analysis

Research
True
Standardized
True
Validated
True
Official
US EPA

Structure recognition assays

Research
Unknown
Standardized
Unknown
Validated
Unknown
Official
n/a

Functional assays

Research
True
Standardized
Unknown
Validated
Unknown
Official
n/a

Animal assays

Research
Unknown
Standardized
Unknown
Validated
Unknown
Official
n/a
Regulatory status
False
Human toxic syndrome(s)
n/a
Organ system toxicity
Hepatotoxicity
Risk assessment
True
Molecular targets known
True
Molecular targets
n/a
Toxic to aquatic animals
True
TEF available
False
Notes
Wade Huang
Contact