β-N-Methylamino-L-alanine

Progenitors

Name

Skeletonema marinoi

Note

Diatoms: A Novel Source for the Neurotoxin BMAA in Aquatic Environments AQC UPLC-MS/MS

Name

Gymnodinium catenatum

Note

BMAA in shellfish from two Portuguese transitional water bodies suggests the marine dinoflagellate Gymnodinium catenatum as a potential BMAA source AQC UPLC-MS/MS

Name

Thalassiosira pseudonana

Note

β-N-methylamino-L-alanine (BMAA) and isomers: Distribution in different food web compartments of Thau lagoon, French Mediterranean Sea AQC UPLC-MS/MS

Name

Leptolyngbya

Note

Strategy for quantifying trace levels of BMAA in cyanobacteria by LC/MS/MS AQC HPLC-MS/MS

Name

Planktoniella blanda

Note

Putative biosynthesis mechanism of the neurotoxin β-N-methylamino-L-alanine in marine diatoms based on a transcriptomics approach HILIC-MS/MS

Name

Thalassiosira gravida

Note

Putative biosynthesis mechanism of the neurotoxin β-N-methylamino-L-alanine in marine diatoms based on a transcriptomics approach HILIC-MS/MS

Name

Thalassiosira

Note

Diatoms: A Novel Source for the Neurotoxin BMAA in Aquatic Environments； Production of BMAA and DAB by diatoms (Phaeodactylum tricornutum, Chaetoceros sp., Chaetoceros calcitrans and, Thalassiosira pseudonana) and bacteria isolated from a diatom culture； Kinetics of β-N-methylamino-L-alanine (BMAA) and 2, 4-diaminobutyric acid (DAB) production by diatoms: the effect of nitrogen; Food web biomagnification of the neurotoxin β-N-methylamino-L-alanine in a diatom-dominated marine ecosystem in China AQC UPLC-MS/MS；HILIC-MS/MS

Name

Chaetoceros

Note

β-N-methylamino-L-alanine (BMAA) and isomers: Distribution in different food web compartments of Thau lagoon, French Mediterranean Sea； Production of BMAA and DAB by diatoms (Phaeodactylum tricornutum, Chaetoceros sp., Chaetoceros calcitrans and, Thalassiosira pseudonana) and bacteria isolated from a diatom culture; Food web biomagnification of the neurotoxin β-N-methylamino-L-alanine in a diatom-dominated marine ecosystem in China AQC UPLC-MS/MS；HILIC-MS/MS

Name

Phaeodactylum tricornutum

Note

β-N-methylamino-L-alanine (BMAA) and isomers: Distribution in different food web compartments of Thau lagoon, French Mediterranean Sea； Production of BMAA and DAB by diatoms (Phaeodactylum tricornutum, Chaetoceros sp., Chaetoceros calcitrans and, Thalassiosira pseudonana) and bacteria isolated from a diatom culture； Kinetics of β-N-methylamino-L-alanine (BMAA) and 2, 4-diaminobutyric acid (DAB) production by diatoms: the effect of nitrogen AQC UPLC-MS/MS；HILIC-MS/MS

Name

Halamphora coffeaeformis

Note

Systematic detection of BMAA (β-N-methylamino-L-alanine) and DAB (2,4-diaminobutyric acid) in mollusks collected in shellfish production areas along the French coasts HILIC-MS/MS

Name

Navicula

Note

Kinetics of β-N-methylamino-L-alanine (BMAA) and 2, 4-diaminobutyric acid (DAB) production by diatoms: the effect of nitrogen AQC UPLC-MS/MS

Name

Chaetoceros decipiens

Note

Food web biomagnification of the neurotoxin β-N-methylamino-L-alanine in a diatom-dominated marine ecosystem in China HILIC-MS/MS

Name

Pseudo-nitzschia lundholmiae

Note

Food web biomagnification of the neurotoxin β-N-methylamino-L-alanine in a diatom-dominated marine ecosystem in China HILIC-MS/MS

Name

Pseudo-nitzschia bipertita

Note

Food web biomagnification of the neurotoxin β-N-methylamino-L-alanine in a diatom-dominated marine ecosystem in China HILIC-MS/MS

Name

Pseudo-nitzschia simulans

Note

Food web biomagnification of the neurotoxin β-N-methylamino-L-alanine in a diatom-dominated marine ecosystem in China HILIC-MS/MS

Name

Pseudo-nitzschia delicatissima

Note

Food web biomagnification of the neurotoxin β-N-methylamino-L-alanine in a diatom-dominated marine ecosystem in China HILIC-MS/MS

Name

Pseudo-nitzschia

Note

Food web biomagnification of the neurotoxin β-N-methylamino-L-alanine in a diatom-dominated marine ecosystem in China HILIC-MS/MS

Name

Pseudo-nitzschia fraudulenta

Note

Food web biomagnification of the neurotoxin β-N-methylamino-L-alanine in a diatom-dominated marine ecosystem in China HILIC-MS/MS

Name

Pseudo-nitzschia multiseries

Note

Food web biomagnification of the neurotoxin β-N-methylamino-L-alanine in a diatom-dominated marine ecosystem in China HILIC-MS/MS

Name

Planktoniella blanda

Note

Food web biomagnification of the neurotoxin β-N-methylamino-L-alanine in a diatom-dominated marine ecosystem in China Putative biosynthesis mechanism of the neurotoxin β-N-methylamino-L-alanine in marine diatoms based on a transcriptomics approach HILIC-MS/MS

Name

Thalassiosira lundiana

Note

Food web biomagnification of the neurotoxin β-N-methylamino-L-alanine in a diatom-dominated marine ecosystem in China Putative biosynthesis mechanism of the neurotoxin β-N-methylamino-L-alanine in marine diatoms based on a transcriptomics approach HILIC-MS/MS

Name

Thalassiosira minima

Note

Putative biosynthesis mechanism of the neurotoxin β-N-methylamino-L-alanine in marine diatoms based on a transcriptomics approach HILIC-MS/MS

Vector Species

Name

Osmerus eperlanus

Note

Transfer of a cyanobacterial neurotoxin within a temperate aquatic ecosystem suggests pathways for human exposure AQC HPLC-MS/MS

Name

Scophthalmus maximus

Note

Transfer of a cyanobacterial neurotoxin within a temperate aquatic ecosystem suggests pathways for human exposure AQC HPLC-MS/MS

Name

Clupea harengus

Note

Transfer of a cyanobacterial neurotoxin within a temperate aquatic ecosystem suggests pathways for human exposure AQC HPLC-MS/MS

Name

Coregonus lavaretus

Note

Transfer of a cyanobacterial neurotoxin within a temperate aquatic ecosystem suggests pathways for human exposure AQC HPLC-MS/MS

Name

Ostrea edulis

Note

Transfer of a cyanobacterial neurotoxin within a temperate aquatic ecosystem suggests pathways for human exposure; Quantification of neurotoxin BMAA (β-N-methylamino-L-alanine) in seafood from Swedish markets AQC HPLC-MS/MS； AQC UPLC-MS/MS

Name

Callinectes sapidus

Note

Cyanobacterial blooms and the occurrence of the neurotoxin, beta-N-methylamino-L-alanine (BMAA), in South Florida aquatic food webs AQC LC-MS/MS

Name

Pinctada margaritifera

Note

Cyanobacterial blooms and the occurrence of the neurotoxin, beta-N-methylamino-L-alanine (BMAA), in South Florida aquatic food webs AQC LC-MS/MS

Name

Sphoeroides parvus

Note

Cyanobacterial blooms and the occurrence of the neurotoxin, beta-N-methylamino-L-alanine (BMAA), in South Florida aquatic food webs AQC LC-MS/MS

Name

Mytilus edulis

Note

Transfer of a cyanobacterial neurotoxin within a temperate aquatic ecosystem suggests pathways for human exposure; Quantification of neurotoxin BMAA (β-N-methylamino-L-alanine) in seafood from Swedish markets； Seafood sold in Sweden contains BMAA: A study of free and total concentrations with UHPLC-MS/MS and dansyl chloride derivatization； A new method for analysis of underivatized free β-methylamino-alanine: Validation and method comparison AQC HPLC-MS/MS； AQC UPLC-MS/MS；DNS HPLC-MS/MS；HILIC UPLC-MS/MS

Name

Pseudorasbora parva

Note

Occurrence and transfer of a cyanobacterial neurotoxin β-methylamino-L-alanine within the aquatic food webs of Gonghu Bay (Lake Taihu, China) to evaluate the potential human health risk AQC HPLC–MS/MS

Name

Rhodeus sinensis

Note

Occurrence and transfer of a cyanobacterial neurotoxin β-methylamino-L-alanine within the aquatic food webs of Gonghu Bay (Lake Taihu, China) to evaluate the potential human health risk AQC HPLC–MS/MS

Name

Panulirus

Note

Detection of cyanobacterial neurotoxin β-N-methylamino-L-alanine within shellfish in the diet of an ALS patient in Florida AQC LC-MS/MS

Name

Corbicula

Note

Biomagnification characteristics and health risk assessment of the neurotoxin BMAA in freshwater aquaculture products of Taihu Lake Basin, China

Name

Sphoeroides spengleri

Note

Cyanobacterial blooms and the occurrence of the neurotoxin, beta-N-methylamino-L-alanine (BMAA), in South Florida aquatic food webs AQC LC-MS/MS

Name

Lutjanus griseus

Note

Cyanobacterial blooms and the occurrence of the neurotoxin, beta-N-methylamino-L-alanine (BMAA), in South Florida aquatic food webs AQC LC-MS/MS

Name

Gerreidae

Note

Cyanobacterial blooms and the occurrence of the neurotoxin, beta-N-methylamino-L-alanine (BMAA), in South Florida aquatic food webs AQC LC-MS/MS

Name

Acanthostracion quadricornis

Note

Cyanobacterial blooms and the occurrence of the neurotoxin, beta-N-methylamino-L-alanine (BMAA), in South Florida aquatic food webs AQC LC-MS/MS

Name

Haemulon parra

Note

Cyanobacterial blooms and the occurrence of the neurotoxin, beta-N-methylamino-L-alanine (BMAA), in South Florida aquatic food webs AQC LC-MS/MS

Name

Alligator

Note

Cyanobacterial blooms and the occurrence of the neurotoxin, beta-N-methylamino-L-alanine (BMAA), in South Florida aquatic food webs AQC LC-MS/MS

Name

Callinectes sapidus

Note

Detection and quantification of β-methylamino-L-alanine in aquatic invertebrates; Linking β-methylamino-L-alanine exposure to sporadic amyotrophic lateral sclerosis in Annapolis, MD AQC LC-MS/MS；AQC HPLC-MS/MS

Name

Mytilus galloprovincialis

Note

Dietary BMAA Exposure in an Amyotrophic Lateral Sclerosis Cluster from Southern France； Ubiquity of the neurotoxin β-N-methylamino-L-alanine and its isomers confirmed by two different mass spectrometric methods in diverse marine mollusks; Food web biomagnification of the neurotoxin β-N-methylamino-L-alanine in a diatom-dominated marine ecosystem in China； Matrix Effect of Diverse Biological Samples Extracted with Different Extraction Ratios on the Detection of β-N-Methylamino-L-Alanine by Two Common LC-MS/MS Analysis Methods AQC UPLC-MS/MS；HILIC-MS/MS

Name

Cerastoderma edule

Note

BMAA in shellfish from two Portuguese transitional water bodies suggests the marine dinoflagellate Gymnodinium catenatum as a potential BMAA source AQC UPLC-MS/MS

Name

Caridea

Note

Quantification of neurotoxin BMAA (β-N-methylamino-L-alanine) in seafood from Swedish markets AQC UPLC-MS/MS

Name

Pleuronectes platessa

Note

Quantification of neurotoxin BMAA (β-N-methylamino-L-alanine) in seafood from Swedish markets AQC UPLC-MS/MS

Name

Clupea harengus

Note

Quantification of neurotoxin BMAA (β-N-methylamino-L-alanine) in seafood from Swedish markets AQC UPLC-MS/MS

Name

Salvelinus alpinus

Note

Quantification of neurotoxin BMAA (β-N-methylamino-L-alanine) in seafood from Swedish markets AQC UPLC-MS/MS

Name

Eriocheir

Note

Occurrence and transfer of a cyanobacterial neurotoxin β-methylamino-L-alanine within the aquatic food webs of Gonghu Bay (Lake Taihu, China) to evaluate the potential human health risk AQC HPLC–MS/MS

Name

Macrobrachium

Note

Occurrence and transfer of a cyanobacterial neurotoxin β-methylamino-L-alanine within the aquatic food webs of Gonghu Bay (Lake Taihu, China) to evaluate the potential human health risk AQC HPLC–MS/MS

Name

Procambarus clarkii

Note

Occurrence and transfer of a cyanobacterial neurotoxin β-methylamino-L-alanine within the aquatic food webs of Gonghu Bay (Lake Taihu, China) to evaluate the potential human health risk AQC HPLC–MS/MS

Name

Carassius auratus

Note

Occurrence and transfer of a cyanobacterial neurotoxin β-methylamino-L-alanine within the aquatic food webs of Gonghu Bay (Lake Taihu, China) to evaluate the potential human health risk AQC HPLC–MS/MS

Name

Cyprinus

Note

Occurrence and transfer of a cyanobacterial neurotoxin β-methylamino-L-alanine within the aquatic food webs of Gonghu Bay (Lake Taihu, China) to evaluate the potential human health risk AQC HPLC–MS/MS

Name

Erythroculter

Note

Occurrence and transfer of a cyanobacterial neurotoxin β-methylamino-L-alanine within the aquatic food webs of Gonghu Bay (Lake Taihu, China) to evaluate the potential human health risk AQC HPLC–MS/MS

Name

Hemiramphus

Note

Occurrence and transfer of a cyanobacterial neurotoxin β-methylamino-L-alanine within the aquatic food webs of Gonghu Bay (Lake Taihu, China) to evaluate the potential human health risk AQC HPLC–MS/MS

Name

Hypophthalmichthys molitrix

Note

Occurrence and transfer of a cyanobacterial neurotoxin β-methylamino-L-alanine within the aquatic food webs of Gonghu Bay (Lake Taihu, China) to evaluate the potential human health risk AQC HPLC–MS/MS

Name

Neosalanx

Note

Occurrence and transfer of a cyanobacterial neurotoxin β-methylamino-L-alanine within the aquatic food webs of Gonghu Bay (Lake Taihu, China) to evaluate the potential human health risk AQC HPLC–MS/MS

Name

Parabramis pekinensis

Note

Occurrence and transfer of a cyanobacterial neurotoxin β-methylamino-L-alanine within the aquatic food webs of Gonghu Bay (Lake Taihu, China) to evaluate the potential human health risk AQC HPLC–MS/MS

Name

Pelteobagrus

Note

Occurrence and transfer of a cyanobacterial neurotoxin β-methylamino-L-alanine within the aquatic food webs of Gonghu Bay (Lake Taihu, China) to evaluate the potential human health risk AQC HPLC–MS/MS

Name

Protosalanx hyalocranius

Note

Occurrence and transfer of a cyanobacterial neurotoxin β-methylamino-L-alanine within the aquatic food webs of Gonghu Bay (Lake Taihu, China) to evaluate the potential human health risk AQC HPLC–MS/MS

Name

Cyprinus carpio

Note

Detection of Cyanotoxins, β-N-methylamino-L-alanine and Microcystins, from a Lake Surrounded by Cases of Amyotrophic Lateral Sclerosis AQC LC-MS/MS

Name

Abramis brama

Note

Biotransfer of β-N-Methylamino-L-alanine (BMAA) in a Eutrophicated Freshwater Lake AQC UPLC-MS/MS

Name

Perca fluviatilis

Note

Biotransfer of β-N-Methylamino-L-alanine (BMAA) in a Eutrophicated Freshwater Lake AQC UPLC-MS/MS

Name

Esox lucius

Note

Biotransfer of β-N-Methylamino-L-alanine (BMAA) in a Eutrophicated Freshwater Lake AQC UPLC-MS/MS

Name

Sander lucioperca

Note

Biotransfer of β-N-Methylamino-L-alanine (BMAA) in a Eutrophicated Freshwater Lake AQC UPLC-MS/MS

Name

Gymnocephalus cernua

Note

Biotransfer of β-N-Methylamino-L-alanine (BMAA) in a Eutrophicated Freshwater Lake AQC UPLC-MS/MS

Name

Anguilla anguilla

Note

Biotransfer of β-N-Methylamino-L-alanine (BMAA) in a Eutrophicated Freshwater Lake AQC UPLC-MS/MS

Name

Perna canaliculus

Note

Seafood sold in Sweden contains BMAA: A study of free and total concentrations with UHPLC-MS/MS and dansyl chloride derivatization DNS UPLC-MS/MS

Name

Placopecten magellanicus

Note

Seafood sold in Sweden contains BMAA: A study of free and total concentrations with UHPLC-MS/MS and dansyl chloride derivatization DNS UPLC-MS/MS

Name

Mytilus

Note

New Typical Vector of Neurotoxin β-N-Methylamino-L-Alanine (BMAA) in the Marine Benthic Ecosystem； Systematic detection of BMAA (β-N-methylamino-L-alanine) and DAB (2,4-diaminobutyric acid) in mollusks collected in shellfish production areas along the French coasts； Ubiquity of the neurotoxin β-N-methylamino-L-alanine and its isomers confirmed by two different mass spectrometric methods in diverse marine mollusks HILIC-MS/MS

Name

Solen strictus

Note

New Typical Vector of Neurotoxin β-N-Methylamino-L-Alanine (BMAA) in the Marine Benthic Ecosystem HILIC-MS/MS

Name

Neverita didyma

Note

New Typical Vector of Neurotoxin β-N-Methylamino-L-Alanine (BMAA) in the Marine Benthic Ecosystem； Ubiquity of the neurotoxin β-N-methylamino-L-alanine and its isomers confirmed by two different mass spectrometric methods in diverse marine mollusks; Food web biomagnification of the neurotoxin β-N-methylamino-L-alanine in a diatom-dominated marine ecosystem in China HILIC-MS/MS

Name

Crassostrea

Note

Quantification of neurotoxin BMAA (β-N-methylamino-L-alanine) in seafood from Swedish markets； Systematic detection of BMAA (β-N-methylamino-L-alanine) and DAB (2,4-diaminobutyric acid) in mollusks collected in shellfish production areas along the French coasts； Ubiquity of the neurotoxin β-N-methylamino-L-alanine and its isomers confirmed by two different mass spectrometric methods in diverse marine mollusks; Food web biomagnification of the neurotoxin β-N-methylamino-L-alanine in a diatom-dominated marine ecosystem in China； Matrix Effect of Diverse Biological Samples Extracted with Different Extraction Ratios on the Detection of β-N-Methylamino-L-Alanine by Two Common LC-MS/MS Analysis Methods AQC LC-MS/MS；HILIC-MS/MS

Name

Phocoena

Note

A collaborative evaluation of LC-MS/MS based methods for BMAA analysis: Soluble bound BMAA found to be an important fraction HILIC-MS/MS

Name

Galeocerdo cuvier

Note

Cyanobacterial Neurotoxin BMAA and Mercury in Sharks AQC UPLC-MS/MS

Name

Chlamys

Note

Ubiquity of the neurotoxin β-N-methylamino-L-alanine and its isomers confirmed by two different mass spectrometric methods in diverse marine mollusks; Food web biomagnification of the neurotoxin β-N-methylamino-L-alanine in a diatom-dominated marine ecosystem in China HILIC-MS/MS

Name

Patinopecten

Note

Ubiquity of the neurotoxin β-N-methylamino-L-alanine and its isomers confirmed by two different mass spectrometric methods in diverse marine mollusks HILIC-MS/MS

Name

Clinocardium

Note

Ubiquity of the neurotoxin β-N-methylamino-L-alanine and its isomers confirmed by two different mass spectrometric methods in diverse marine mollusks HILIC-MS/MS

Name

Ruditapes philippinarum

Note

Ubiquity of the neurotoxin β-N-methylamino-L-alanine and its isomers confirmed by two different mass spectrometric methods in diverse marine mollusks; Food web biomagnification of the neurotoxin β-N-methylamino-L-alanine in a diatom-dominated marine ecosystem in China HILIC-MS/MS

Name

Mactra

Note

Ubiquity of the neurotoxin β-N-methylamino-L-alanine and its isomers confirmed by two different mass spectrometric methods in diverse marine mollusks HILIC-MS/MS

Name

Atrina pectinata

Note

Ubiquity of the neurotoxin β-N-methylamino-L-alanine and its isomers confirmed by two different mass spectrometric methods in diverse marine mollusks; Food web biomagnification of the neurotoxin β-N-methylamino-L-alanine in a diatom-dominated marine ecosystem in China HILIC-MS/MS

Name

Mactra

Note

Ubiquity of the neurotoxin β-N-methylamino-L-alanine and its isomers confirmed by two different mass spectrometric methods in diverse marine mollusks HILIC-MS/MS

Name

Callista chinensis

Note

Ubiquity of the neurotoxin β-N-methylamino-L-alanine and its isomers confirmed by two different mass spectrometric methods in diverse marine mollusks HILIC-MS/MS

Name

Dosinia japonica

Note

Ubiquity of the neurotoxin β-N-methylamino-L-alanine and its isomers confirmed by two different mass spectrometric methods in diverse marine mollusks HILIC-MS/MS

Name

Tegillarca granosa

Note

Ubiquity of the neurotoxin β-N-methylamino-L-alanine and its isomers confirmed by two different mass spectrometric methods in diverse marine mollusks HILIC-MS/MS

Name

Saxidomus purpurata

Note

Ubiquity of the neurotoxin β-N-methylamino-L-alanine and its isomers confirmed by two different mass spectrometric methods in diverse marine mollusks HILIC-MS/MS

Name

Callista

Note

Ubiquity of the neurotoxin β-N-methylamino-L-alanine and its isomers confirmed by two different mass spectrometric methods in diverse marine mollusks HILIC-MS/MS

Name

Cyclina sinensis

Note

Ubiquity of the neurotoxin β-N-methylamino-L-alanine and its isomers confirmed by two different mass spectrometric methods in diverse marine mollusks HILIC-MS/MS

Name

Gomphina

Note

Ubiquity of the neurotoxin β-N-methylamino-L-alanine and its isomers confirmed by two different mass spectrometric methods in diverse marine mollusks HILIC-MS/MS

Name

Mercenaria mercenaria

Note

Ubiquity of the neurotoxin β-N-methylamino-L-alanine and its isomers confirmed by two different mass spectrometric methods in diverse marine mollusks HILIC-MS/MS

Name

Solen strictus

Note

Ubiquity of the neurotoxin β-N-methylamino-L-alanine and its isomers confirmed by two different mass spectrometric methods in diverse marine mollusks HILIC-MS/MS

Name

Meretrix meretrix

Note

Ubiquity of the neurotoxin β-N-methylamino-L-alanine and its isomers confirmed by two different mass spectrometric methods in diverse marine mollusks HILIC-MS/MS

Name

Mactra chinensis

Note

Ubiquity of the neurotoxin β-N-methylamino-L-alanine and its isomers confirmed by two different mass spectrometric methods in diverse marine mollusks HILIC-MS/MS

Name

Neptunea arthritica

Note

Ubiquity of the neurotoxin β-N-methylamino-L-alanine and its isomers confirmed by two different mass spectrometric methods in diverse marine mollusks HILIC-MS/MS

Name

Neptunea

Note

Ubiquity of the neurotoxin β-N-methylamino-L-alanine and its isomers confirmed by two different mass spectrometric methods in diverse marine mollusks HILIC-MS/MS

Name

Neptunea cumingii

Note

Ubiquity of the neurotoxin β-N-methylamino-L-alanine and its isomers confirmed by two different mass spectrometric methods in diverse marine mollusks HILIC-MS/MS

Name

Laguncula pulchella

Note

Ubiquity of the neurotoxin β-N-methylamino-L-alanine and its isomers confirmed by two different mass spectrometric methods in diverse marine mollusks HILIC-MS/MS

Name

Rapana venosa

Note

Ubiquity of the neurotoxin β-N-methylamino-L-alanine and its isomers confirmed by two different mass spectrometric methods in diverse marine mollusks HILIC-MS/MS

Name

Reishia luteostoma

Note

Ubiquity of the neurotoxin β-N-methylamino-L-alanine and its isomers confirmed by two different mass spectrometric methods in diverse marine mollusks HILIC-MS/MS

Name

Turbo

Note

Ubiquity of the neurotoxin β-N-methylamino-L-alanine and its isomers confirmed by two different mass spectrometric methods in diverse marine mollusks HILIC-MS/MS

Name

Asterias amurensis

Note

Ubiquity of the neurotoxin β-N-methylamino-L-alanine and its isomers confirmed by two different mass spectrometric methods in diverse marine mollusks HILIC-MS/MS

Name

Smilium scorpio

Note

Ubiquity of the neurotoxin β-N-methylamino-L-alanine and its isomers confirmed by two different mass spectrometric methods in diverse marine mollusks HILIC-MS/MS

Name

Macrobrachium

Note

Biomagnification characteristics and health risk assessment of the neurotoxin BMAA in freshwater aquaculture products of Taihu Lake Basin, China AQC HPLC-MS/MS

Name

Eriocheir sinensis

Note

Biomagnification characteristics and health risk assessment of the neurotoxin BMAA in freshwater aquaculture products of Taihu Lake Basin, China AQC HPLC-MS/MS

Name

Ctenopharyngodon idella

Note

Biomagnification characteristics and health risk assessment of the neurotoxin BMAA in freshwater aquaculture products of Taihu Lake Basin, China AQC HPLC-MS/MS

Name

Mylopharyngodon piceus

Note

Biomagnification characteristics and health risk assessment of the neurotoxin BMAA in freshwater aquaculture products of Taihu Lake Basin, China AQC HPLC-MS/MS

Name

Sinonovacula constricta

Note

Food web biomagnification of the neurotoxin β-N-methylamino-L-alanine in a diatom-dominated marine ecosystem in China HILIC-MS/MS

Name

Solenocera melantho

Note

Food web biomagnification of the neurotoxin β-N-methylamino-L-alanine in a diatom-dominated marine ecosystem in China HILIC-MS/MS

Name

Zoarces elongatus

Note

Food web biomagnification of the neurotoxin β-N-methylamino-L-alanine in a diatom-dominated marine ecosystem in China HILIC-MS/MS

Name

Patinopecten

Note

Matrix Effect of Diverse Biological Samples Extracted with Different Extraction Ratios on the Detection of β-N-Methylamino-L-Alanine by Two Common LC-MS/MS Analysis Methods HILIC-MS/MS

References

Jiang, L., 2014

Diatoms: A Novel Source for the Neurotoxin BMAA in Aquatic Environments

Zhao, P., 2022

Matrix Effect of Diverse Biological Samples Extracted with Different Extraction Ratios on the Detection of β-N-Methylamino-L-Alanine by Two Common LC-MS/MS Analysis Methods

Jonasson, S., 2010

Transfer of a cyanobacterial neurotoxin within a temperate aquatic ecosystem suggests pathways for human exposure

Brand, L. E., 2010

Cyanobacterial blooms and the occurrence of the neurotoxin, beta-N-methylamino-L-alanine (BMAA), in South Florida aquatic food webs

Christensen, Stephanie J., 2012

Detection and quantification of β-methylamino-L-alanine in aquatic invertebrates

Contardo-Jara, V., 2013

Linking β-methylamino-L-alanine exposure to sporadic amyotrophic lateral sclerosis in Annapolis, MD

Jiang, L., 2013

Strategy for quantifying trace levels of BMAA in cyanobacteria by LC/MS/MS

Jiang, L., 2013

Strategy for quantifying trace levels of BMAA in cyanobacteria by LC/MS/MS

Masseret, E., 2013

Dietary BMAA Exposure in an Amyotrophic Lateral Sclerosis Cluster from Southern France

Lage, S., 2014

BMAA in shellfish from two Portuguese transitional water bodies suggests the marine dinoflagellate Gymnodinium catenatum as a potential BMAA source

Jiang, L., 2014

Quantification of neurotoxin BMAA (β-N-methylamino-L-alanine) in seafood from Swedish markets

Jiao, Y., 2014

Occurrence and transfer of a cyanobacterial neurotoxin β-methylamino-L-alanine within the aquatic food webs of Gonghu Bay (Lake Taihu, China) to evaluate the potential human health risk

Banack, S. A., 2014

Detection of cyanobacterial neurotoxin β-N-methylamino-L-alanine within shellfish in the diet of an ALS patient in Florida

Banack, S. A., 2015

Detection of Cyanotoxins, β-N-methylamino-L-alanine and Microcystins, from a Lake Surrounded by Cases of Amyotrophic Lateral Sclerosis

Lage, S., 2015

Biotransfer of β-N-Methylamino-L-alanine (BMAA) in a Eutrophicated Freshwater Lake

Salomonsson, M. L., 2015

Seafood sold in Sweden contains BMAA: A study of free and total concentrations with UHPLC-MS/MS and dansyl chloride derivatization

Reveillon, D., 2015

β-N-methylamino-L-alanine (BMAA) and isomers: Distribution in different food web compartments of Thau lagoon, French Mediterranean Sea

Li, A., 2016

New Typical Vector of Neurotoxin β-N-Methylamino-L-Alanine (BMAA) in the Marine Benthic Ecosystem

Reveillon, D., 2016

Production of BMAA and DAB by diatoms (Phaeodactylum tricornutum, Chaetoceros sp., Chaetoceros calcitrans and, Thalassiosira pseudonana) and bacteria isolated from a diatom culture

Reveillon, D., 2016

Systematic detection of BMAA (β-N-methylamino-L-alanine) and DAB (2,4-diaminobutyric acid) in mollusks collected in shellfish production areas along the French coasts

Edwards, C., 2016

A collaborative evaluation of LC-MS/MS based methods for BMAA analysis: Soluble bound BMAA found to be an important fraction

Rosén, J., 2016

A new method for analysis of underivatized free β-methylamino-alanine: Validation and method comparison

Lage, Sandra, 2018

Kinetics of β-N-methylamino-L-alanine (BMAA) and 2, 4-diaminobutyric acid (DAB) production by diatoms: the effect of nitrogen

Li, A., 2018

Ubiquity of the neurotoxin β-N-methylamino-L-alanine and its isomers confirmed by two different mass spectrometric methods in diverse marine mollusks

Wu, X., 2019

Biomagnification characteristics and health risk assessment of the neurotoxin BMAA in freshwater aquaculture products of Taihu Lake Basin, China

Wang, C., 2021

Food web biomagnification of the neurotoxin β-N-methylamino-L-alanine in a diatom-dominated marine ecosystem in China

Li, A., 2023

Putative biosynthesis mechanism of the neurotoxin β-N-methylamino-L-alanine in marine diatoms based on a transcriptomics approach

Structure

Formula

C4H10N2O2

Exact mono-isotopic mass

118.0742

Molfile

n/a

Alternative molfiles

n/a

SMILES

CNCC(N)C(O)=O

Alternative SMILES

CNC[C@H](N)C(O)=O

InChi key

UJVHVMNGOZXSOZ-VKHMYHEASA-N

Alternative InChi keys

n/a

InChi

InChI=1S/C4H10N2O2/c1-6-2-3(5)4(7)8/h3,6H,2,5H2,1H3,(H,7,8)/t3-/m0/s1

Alternative InChis

Spectra available

Unknown

Chem files

References

A. Vega, 1967

α-Amino-β-methylaminopropionic acid, a new amino acid from seeds of Cycas circinalis

Nunn, P. B., 1989

The interaction of β-N-methylamino-L-alanine with bicarbonate: an 1H-NMR study

Certified

False

Certified links

n/a

Non certified reference material

Unknown

Chemical analysis

Research

True

Standardized

False

Validated

True

Official

n/a

Structure recognition assays

Research

True

Standardized

Unknown

Validated

Unknown

Official

n/a

Functional assays

Research

Unknown

Standardized

Unknown

Validated

Unknown

Official

n/a

Animal assays

Research

True

Standardized

False

Validated

True

Official

n/a

References

Li, A., 2018

Ubiquity of the neurotoxin β-N-methylamino-L-alanine and its isomers confirmed by two different mass spectrometric methods in diverse marine mollusks

Regulatory status

False

Human toxic syndrome(s)

n/a

Organ system toxicity

Neurotoxicity

Risk assessment

True

Molecular targets known

Unknown

Molecular targets

n/a

Toxic to aquatic animals

True

TEF available

Unknown

Risk assessment References

Wu, X., 2019

Biomagnification characteristics and health risk assessment of the neurotoxin BMAA in freshwater aquaculture products of Taihu Lake Basin, China

Notes

Philipp Hess

Contact

Aifeng Li

Contact

Christopher Miles

Contact